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concern

Skin Barrier

The protective outer layer that keeps moisture in and irritants out.

Evidence: strong

The skin barrier (stratum corneum + lipid matrix) defends against water loss, irritants, and pathogens. When compromised, skin becomes dry, sensitive, and reactive.

Overview

The barrier is a brick-and-mortar structure of corneocytes (bricks) and lipids (mortar: ceramides, cholesterol, fatty acids).

Connected Concepts

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